Kathryn Haas

Faculty Profiles

Kathryn Haas, chemistry professor

Kathryn Haas

Associate Professor
Chemistry Physics
172 Science Hall



Post-doctoral research, National Institutes of Health, National Institute of Environmental Health Sciences, Laboratory of Toxicology and Pharmacology

PhD, Duke University

BS, Gettysburg College


Areas of Expertise 

  • Bio-inorganic chemistry
  • Inorganic chemistry
  • Spectroscopy
  • Peptide synthesis

Research Interests 

  • Characterization of metal-protein interactions
  • Human copper transport
  • Neurodegenerative disease
  • Molecular toxicology

Courses Recently Taught 

  • CHEM 118: General, organic, and biochemistry
  • CHEM 221: Organic chemistry I
  • CHEM 342: Bio-inorganic chemistry and materials
  • CHEM 431: Advanced inorganic chemistry
  • CHEM 485: Research

Professional Experience 

  • Indiana University South Bend, Visiting Assistant Professor, Department of Chemistry & Biochemistry, Spring 2012
  • Polish Academy of Science, Institute of Biochemistry and Biophysics, Visiting Research Professor, collaboration with Dr. Wojciech Bal, Summer 2016

Creative and Scholarly Work 

  • Pushie, M.J.*, Stefaniak, E.; Sendzik, M.; Sokaras, D.; Kroll, T.; Haas, K.*, Using N-terminal Coordination of Cu(II) and Ni(II) to Isolate the Coordination Environment of Cu(I) and Cu(II) Bound to His13 and His14 in Amyloid-β(4-16). Inorganic Chemistry 2019, In press.
  • Stefaniak, E.; Plonka, D.; Drew, S.C.; Haas, K.L.; Pushie, M.J.; Faller, P; Wezynfeld, N.E.; Bal, W., The Nterminal 14-mer peptide of human Ctr1 can collect Cu(II) from albumin. Implications for copper uptake by Ctr1. Metallomics 2018, 10, 1723-1727.
  • Haas, K.L.; Heemstra, J.M.; Medema, M.H.;Charkoudian, L.K., Collaborating with Undergraduates to Contribute to Biochemistry Community Resources. Biochemistry 2018 57 (4), 383-389.
  • Sendzik, M.; Pushie, M.J.; Stefaniak, E.; Haas,K.L., Structure and Affinity of Cu(I) Bound to Human Serum Albumin. Inorg. Chem. 2017, 56 (24), 15057-15065.
  • Larsen, D. S.; Rusay, R.; Belford, R.; Kennepohl, D.; Bennett, D.; Soult, A.; McCollum, B.; Keasler, S.; Halpern, J.; Soderberg, T.; Kosti, K.; Stockwell, W. R.; Haas, K.; Morsch, L. A., Come Join the Party!: Recent Progress of the Community Based Libretexts (NéE Chemwiki) Project. American Chemical Society Division of Chemical Education Committee on Computers in Chemical Education 2017, Spring Newsletter.
  •  Conklin, S.E.; Bridgman, E.; Su, Q.; Riggs-Gelasco, P.; Haas, K.L.; Franz, K.J., Specific Histidine Residues Confer Histatin Peptides with Copper-Dependent Activity against Candida albicans. Biochemistry 2017, 56 (32), 4244-4255.
  • Schwab, S.; Shearer,J.; Conklin, S.E.; Alies, B.;Haas, K.L.*, Sequence proximity between Cu(II) and Cu(I) binding sites of human copper transporter 1 model peptides defines reactivity with ascorbate and O2. J. Inorg. Biochem. 2016, 158, 70-76.
  • Pushie, M. Jake, Katharine Shaw, Katherine J. Franz, Jason Shearer, K. L Haas. “Model Peptide Studies Reveal a Mixed Histidine Methionine Cu(I) Binding Site at the N-Terminus of Human Copper Transporter 1.” Inorganic Chemistry (2015): DOI 10.1021/acs.inorgchem.5b01162.
  • Hall, Julie, Kathryn L. Haas, Jonathan Freedman. “Role of MTL-1, MTL-2 and CDR-1 in Mediating Cadmium Sensitivity in C. elegans.” Toxicological Sciences (2012): DOI 10.1093/toxsci/kfs166.
  • Haas, Kathryn L., Allison B. Putterman, Daniel R. White, Dennis J. Thiele, Katherine J. Franz. “New Insights into hCtr1 function and the role of Histidine in Human Cellular Copper Acquisition.” J. Am. Chem. Soc. (2011): 133 (12), 4427-4437.
  • Haas, Kathryn L., Katherine J. Franz. “Application of metal coordination chemistry to explore and manipulate cell biology.” Chemical Reviews (2009): 109 (10), 4921-4960.
  • Ciesienski, Katie L., Kathryn L. Haas, Marina G. Dickens, Yohannes T. Tesema, Katherine J. Franz. “A photolabile ligand for light-activated release of caged copper.” Journal of the American Chemical Society (2008): 130 (37), 12246.
  • Charkoudian, Louise K., Jared J. Heymann, Marc J. Alder, Kathryn L. Haas, Kassy A. Mies, James F. Bonk. “Forensics as a gateway: Promoting undergraduate interest in science and graduate student professional development through a first-year seminar course.” Journal of Chemical Education (2008): 85 (6), 807.

Professional Memberships 

The American Chemical Society, 2004-present
Council for Undergraduate Research, 2013-present
Chemistry Women Mentorship Network, 2014-present
Society of Toxicology, 2011-2012