Faculty Profiles

Rana Abdel-Samad

Rana Abdel-Samad

Assistant Professor
Science Hall 276



  • PhD, Institute of Functional Genomics and University of Montpellier II, France
  • BA, Saint-Joseph University, Lebanon

Areas of Expertise 

  • Cancer Research
  • Human Cell Culture
  • Protein Biochemistry

Research Interests 

  • Anti-cancer activity of retinoid molecules in colorectal cancer cells
  • Effect of the novel polymerase alpha-HDAC11 inhibitor on the proliferation of colorectal cancer cells
  • Protein interactions of SOX9 transcription factor in colorectal cancer

Courses Recently Taught 

  • BIO317 – Microbiology
  • BIO317L – Microbiology lab
  • BIO202 – Global Challenges in Infectious Diseases

Creative and Scholarly Work 

  • Abdel-Samad R, Aouad P, Darwiche N. Natural and synthetic retinoids in preclinical colorectal cancer models. Anticancer Drugs. 2019 Aug;30(7):e0802.
  • Abdel-Samad R, Aouad P, Gali-Muhtasib H, Sweidan Z, Hmadi R, Kadara H, et al. Mechanism of action of the atypical retinoid ST1926 in colorectal cancer: DNA damage and DNA polymerase α. Am J Cancer Res. 2018 Jan 1;8(1):39-55
  • Aouad P, Saikali M, Abdel-Samad R, Fostok S, El-Houjeiri L, Pisano C, Talhouk R, Darwiche N. Antitumor activities of the synthetic retinoid ST1926 in two-dimensional and three-dimensional human breast cancer models. Anticancer Drugs. 2017 Aug;28(7):757-770.
  • Karam L, Houshaymi B, Abdel-Samad R, Jaafar M, Halloum I, Pisano C, Neipel F, Darwiche N, Abou Merhi R. Antitumor activity of the synthetic retinoid ST1926 on primary effusion lymphoma in vitro and in vivo models. Oncol Rep. 2018 Feb;39(2):721-730.
  • Abdel-Samad R, Zalzali H, Rammah C, Giraud J, Naudin C, Dupasquier S, et al. MiniSOX9, a dominant-negative variant in colon cancer cells. Oncogene. 2011 Jun 2;30(22):2493-503.
  • Dupasquier S, Abdel-Samad R, Glazer RI, Bastide P, Jay P, Joubert D, et al. A new mechanism of SOX9 action to regulate PKCalpha expression in the intestine epithelium. J Cell Sci. 2009 Jul 1;122(Pt 13):2191-6.